Adult onset stills disease
AOSD is a rare type of inflammatory arthritis that causes inflammation resulting in joint damage, high fevers and rashes. AOSD mainly develops in people between the ages of The main symptoms of AOSD include daily high fevers, skin rashes and painful, swollen joints. The signs and symptoms of AOSD can be very similar to those of other serious conditions, including other autoinflammatory syndromes, systemic lupus erythematosus lupus and a type of blood cancer called lymphoma. Some people may only experience one bout of the illness and will not go on to experience another flare, while in others the disease persists and may lead to permanent joint destruction.
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Adult-onset Still's disease
AOSD: Adult-onset Still’s Disease - Symptoms & Causes
This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly.
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Adult-Onset Still's Disease
AOSD is an inflammatory condition that can cause exhaustion and swelling in your joints, tissues, organs, and lymph nodes. This condition goes through episodes of flare-up and remission: Symptoms can appear and disappear suddenly. They also sometimes never come back.
The U. AOSD is a rare and serious autoinflammatory disease of unknown origin. Autoinflammatory diseases are caused by abnormalities of the immune system, which trigger an inflammatory response that can damage the body's own tissues. Ilaris works by blocking the effects of IL-1 and suppressing inflammation in patients with this autoinflammatory disorder. The safety and efficacy of Ilaris for the treatment of patients with AOSD was established using comparable pharmacokinetic exposure and extrapolation of established efficacy of canakinumab in patients with SJIA, as well as the safety of canakinumab in patients with AOSD and other diseases.
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